THIAMIN PRODUCTION BY FERMENTATION

The present invention provides a method for producing thiamin products using a microorganism containing a mutation that causes it to overproduce and release thiamin products into the medium. Biologically pure cultures of the microorganisms and isolated polynucleotides containing the mutations are al...

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Bibliographische Detailangaben
Hauptverfasser:	SCHYNS, GHISLAIN, PERKINS, JOHN, B, GOESE, MARKUS, GUENTER
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides a method for producing thiamin products using a microorganism containing a mutation that causes it to overproduce and release thiamin products into the medium. Biologically pure cultures of the microorganisms and isolated polynucleotides containing the mutations are also provided. In addition, methods for detecting a pathogenic microorganism in a clinical sample, assays for identifying an antibiotic, as well as, antibiotics identified by such assays are provided. L'invention concerne un procédé pour l'élaboration de produits de thiamine faisant appel à un micro-organisme qui contient une mutation induisant la suproduction et la libération des produits de thiamine dans le milieu. L'invention concerne également des cultures biologiquement pures relatives aux micro-organismes de ce type et des polynucléotides isolés renfermant les mutations considérées. L'invention concerne en outre des procédés de détection de micro-organisme pathogène dans un échantillon clinique, des essais pour l'identification d'antibiotiques, ainsi que des antibiotiques identifiés au moyen de ces essais.