BIOACTIVE PEPTIDE-PRODUCING STRAINS OF ENTEROCOCCUS FAECALIS, BIOACTIVE PEPTIDES AND APPLICATIONS THEREOF

The invention relates to Enterococcus faecalis bacteria which can produce bioactive peptides, such as peptides with angiotensin-converting enzyme-inhibiting activity and/or antihypertensive activity. The aforementioned bacteria can be used to ferment a substrate comprising one or more proteins, pept...

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Bibliographische Detailangaben
Hauptverfasser:	QUIROS DEL BOSQUE, ANA, RECIO SANCHEZ, ISIDRA, ALEIXANDRE DE ARTINANO, MA, AMAYA, RAMOS GONZALEZ, MERCEDES, MUGUERZA MARQUINEZ, BEGONA, DELGADO DELGADO, MARCO ANTONIO
Format:	Patent
Sprache:	eng ; fre ; spa
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to Enterococcus faecalis bacteria which can produce bioactive peptides, such as peptides with angiotensin-converting enzyme-inhibiting activity and/or antihypertensive activity. The aforementioned bacteria can be used to ferment a substrate comprising one or more proteins, peptides or fragments of same which contain the amino acid sequence of said bioactive peptides. Moreover, the above-mentioned bacteria and bioactive peptides can be used in the pharmaceutical and food industries for the preparation of pharmaceutical compositions or functional food products. La bacteria Enterococcus faecalis tiene la capacidad de producir péptidos bioactivos, tales como péptidos con actividad inhibidora de la enzima convertidora de la angiotensina y/o con actividad antihipertensiva. Dicha bacteria puede utilizarse para fermentar un sustrato que comprende una o más proteínas, péptidos bioactivos. Dicha bacteria y dichos péptidos bioactivos pueden ser utilizados en la industria farmacéutica y alimentaria, en la elaboración de composiciones farmacéuticas o productos alimentarios funcionales. L'invention concerne la bactérie Enterococcus faecalis, laquelle est capable de produire des peptides bioactifs, tels que des peptides présentant une activité d'inhibition de l'enzyme de conversion de l'angiotensine et/ou une activité d'antihypertension. Cette bactérie peut être utilisée pour faire fermenter un substrat qui comprend une ou plusieurs protéines, des peptides bioactifs. Cette bactérie et ces peptides bioactifs peuvent être utilisés dans l'industrie pharmaceutique et alimentaire, dans l'élaboration de compositions pharmaceutiques ou de produits alimentaires fonctionnels.