BENZOXAZINONE DERIVATIVES, THEIR PREPARATION AND USE

BENZOXAZINONE DERIVATIVES, THEIR PREPARATION AND USE

Compounds of formula (I) and pharmaceutically acceptable salts thereof are disclosed, wherein R1 is hydrogen or C1-6alkyl; and R2 is fluoro or chloro. Methods of preparation and uses thereof in treatment of CNS disorders, such as depression or anxiety, are also disclosed. L'invention concerne d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: VONG, ANTONIO, KUOK, KEONG, WARD, SIMON, EDWARD
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Compounds of formula (I) and pharmaceutically acceptable salts thereof are disclosed, wherein R1 is hydrogen or C1-6alkyl; and R2 is fluoro or chloro. Methods of preparation and uses thereof in treatment of CNS disorders, such as depression or anxiety, are also disclosed. L'invention concerne des composés de formule (I) et des sels pharmaceutiquement acceptables de ceux-ci : (I), dans laquelle R1 représente hydrogène ou alkyle C1-6 ; et R2 représente fluoro ou chloro. L'invention concerne également des procédés de préparation, ainsi que les utilisations desdits composés dans le traitement des troubles du système nerveux central, tels que la dépression ou l'angoisse.