BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS

The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula (1). Wherein Z, X, R , R , R , and R are as described in s...

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Bibliographische Detailangaben
Hauptverfasser:	BROWN, DAVID, LOUIS, TALLEY, JOHN, J, YU, YI, HAMPER, BRUCE, CAMERON, KOSZYK, FRANCIS, WANG, LIJUAN, JANE, HALLINAN, E., ANN, SPRINGER, JOHN, ROBERT, ASTON, KARL, WILLIAM, KIEFER, JAMES, RICHARD, JR, XING, LI, LIAO, SUBO, DEPROW, ANGELA, LIMBURG, DAVID, CHRISTOPHER, MCCALL, JOHN, MICHAEL, CARTER, JEFFERY, STEVEN, LUDWIG, CINDY, FLETCHER, THERESA, HUFF, RENEE, KRAMER, STEVEN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula (1). Wherein Z, X, R , R , R , and R are as described in specification. La présente invention se rapporte à des procédés et des composés utilisables dans le traitement d'une pathologie associée à des troubles à médiation par cyclo-oxygénase-2. Parmi les composés présentant un intérêt particulier se trouvent les benzopyranes et leurs analogues définis par la formule I, dans laquelle Z, X, R , R , R et R ont la notation donnée dans la description.