USE OF TANSHINONE DERIVATES AS CHOLINESTERASE INHIBITORS IN TREATING RELATED DISEASES

This present invention provides a new use of tanshinone derivatives as acetylcholinesterase inhibitors and in treating diseases associated with the depletion of acetylcholine such as cognitive impairment including Alzheimer's disease, insomnia, vascular dementia, memory loss, disorders of atten...

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Hauptverfasser: WAN, DAVID, CHIONG, SHAW, PANGUI, FUNG, KWOK-PUI, HO, MICHELLE TSZ-WAN
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creator WAN, DAVID, CHIONG
SHAW, PANGUI
FUNG, KWOK-PUI
HO, MICHELLE TSZ-WAN
description This present invention provides a new use of tanshinone derivatives as acetylcholinesterase inhibitors and in treating diseases associated with the depletion of acetylcholine such as cognitive impairment including Alzheimer's disease, insomnia, vascular dementia, memory loss, disorders of attention, and other sleeping disorders. The active compounds are commonly found in the root of Salvia genus, particularly Salvia miltiorrhiza, Danshen. L'invention concerne une nouvelle utilisation de dérivés de tanshinone en tant qu'inhibiteurs d'acétylcholinestérase et pour le traitement de maladies associées à l'appauvrissement en acétylcholine telles qu'un déficit cognitif, y compris la maladie d'Alzheimer, l'insomnie, les troubles cérébraux vasculaires, les pertes de mémoire, les troubles de l'attention ou d'autres troubles du sommeil. On trouve communément les composés actifs dans la racine du genre Salvia en particulier, Salvia miltiorrhiza, Danshen.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title USE OF TANSHINONE DERIVATES AS CHOLINESTERASE INHIBITORS IN TREATING RELATED DISEASES
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