USE OF TANSHINONE DERIVATES AS CHOLINESTERASE INHIBITORS IN TREATING RELATED DISEASES

This present invention provides a new use of tanshinone derivatives as acetylcholinesterase inhibitors and in treating diseases associated with the depletion of acetylcholine such as cognitive impairment including Alzheimer's disease, insomnia, vascular dementia, memory loss, disorders of atten...

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Bibliographische Detailangaben
Hauptverfasser:	WAN, DAVID, CHIONG, SHAW, PANGUI, FUNG, KWOK-PUI, HO, MICHELLE TSZ-WAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This present invention provides a new use of tanshinone derivatives as acetylcholinesterase inhibitors and in treating diseases associated with the depletion of acetylcholine such as cognitive impairment including Alzheimer's disease, insomnia, vascular dementia, memory loss, disorders of attention, and other sleeping disorders. The active compounds are commonly found in the root of Salvia genus, particularly Salvia miltiorrhiza, Danshen. L'invention concerne une nouvelle utilisation de dérivés de tanshinone en tant qu'inhibiteurs d'acétylcholinestérase et pour le traitement de maladies associées à l'appauvrissement en acétylcholine telles qu'un déficit cognitif, y compris la maladie d'Alzheimer, l'insomnie, les troubles cérébraux vasculaires, les pertes de mémoire, les troubles de l'attention ou d'autres troubles du sommeil. On trouve communément les composés actifs dans la racine du genre Salvia en particulier, Salvia miltiorrhiza, Danshen.