PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS

The invention provides pharmaceutical compositions comprising a cholesteryl ester transfer protein (CETP) inhibitor and a water-insoluble concentration-enhancing additive, which exhibit improved bioavailability. The invention also provides methods of treating cardiovascular disorders comprising the...

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Hauptverfasser: SUNAMI, MASAKI, SERIGANO, TAKANORI
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creator SUNAMI, MASAKI
SERIGANO, TAKANORI
description The invention provides pharmaceutical compositions comprising a cholesteryl ester transfer protein (CETP) inhibitor and a water-insoluble concentration-enhancing additive, which exhibit improved bioavailability. The invention also provides methods of treating cardiovascular disorders comprising the administration of the pharmaceutical compositions comprising a CETP inhibitor. Cette invention se rapporte à des compositions pharmaceutiques comprenant un inhibiteur de protéine de transfert de cholestéryl-ester (CETP) et un additif d'amélioration de concentration insoluble dans l'eau, qui possèdent une biodisponibilité améliorée. Cette invention concerne également des procédés pour traiter des troubles cardio-vasculaires, consistant à administrer ces compositions pharmaceutiques comprenant un inhibiteur de CETP.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS
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