PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS

The invention provides pharmaceutical compositions comprising a cholesteryl ester transfer protein (CETP) inhibitor and a water-insoluble concentration-enhancing additive, which exhibit improved bioavailability. The invention also provides methods of treating cardiovascular disorders comprising the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	SUNAMI, MASAKI, SERIGANO, TAKANORI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The invention provides pharmaceutical compositions comprising a cholesteryl ester transfer protein (CETP) inhibitor and a water-insoluble concentration-enhancing additive, which exhibit improved bioavailability. The invention also provides methods of treating cardiovascular disorders comprising the administration of the pharmaceutical compositions comprising a CETP inhibitor. Cette invention se rapporte à des compositions pharmaceutiques comprenant un inhibiteur de protéine de transfert de cholestéryl-ester (CETP) et un additif d'amélioration de concentration insoluble dans l'eau, qui possèdent une biodisponibilité améliorée. Cette invention concerne également des procédés pour traiter des troubles cardio-vasculaires, consistant à administrer ces compositions pharmaceutiques comprenant un inhibiteur de CETP.