STEREOSELECTIVE CHEMOENZYMATIC PROCESS FOR PREPARING OPTICALLY ENRICHED PHENYLGLYCIDATES

The present invention relates to a novel and efficient chemoenzymatic process of preparation of optically active trans alkyl phenylglycidates. The invention particularly discloses a novel process for the chemoenzymatic synthesis of two enantiomers of trans alkyl phenylglycidate i.e. alkyl(2S,3R)-phe...

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Bibliographische Detailangaben
Hauptverfasser: KOUL, SURRINDER, ANAND, NAVEEN, KAPOOR, MUNISH, TANEJA, SUBHASH, CHANDRA, SHARMA, RATAN, LAL, QAZI, GULAM, NABI
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to a novel and efficient chemoenzymatic process of preparation of optically active trans alkyl phenylglycidates. The invention particularly discloses a novel process for the chemoenzymatic synthesis of two enantiomers of trans alkyl phenylglycidate i.e. alkyl(2S,3R)-phenylglycidate and alkyl(2R,3S)-phenylglycidate of formulae 7 and 8 respectively. La présente invention concerne un nouveau procédé chimioenzymatique efficace destiné à la préparation de trans-alkyle-phénylglycidates optiquement actifs. L'invention se rapporte plus particulièrement à un nouveau procédé de synthèse chimioenzymatique de deux énantiomères de trans-alkyle-phénylglycidate, c'est-à-dire alkyl(2S,3R)-phénylglycidate et alkyl(2R,3S)-phénylglycidate, répondant respectivement aux formules 7 et 8.