THE USE OF 4-PHENYL SUBSTITUTED TETRAHYDROISOQUINOLINES IN THE TREATMENT OF PAIN, MIGRAINE AND URINARY INCONTINENCE

Provided herein are methods of using compounds of formula (IA, IB, IIA, IIB, IIIA, IIIB) that are aryl- and heteroaryl-substituted tetrahydroisoquinolines, for the treatment of chronic and neuropathic pain, the treatment and prevention of migraine headache, and the treatment of stress, urge and mixe...

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Bibliographische Detailangaben
Hauptverfasser:	FRAIL, DONALD, EDWARD, ARNERIC, STEPHEN, PETER, WISHKA, DONN, GREGORY, WONG, ERIK, HO, FONG, BECK, JAMES, PETER
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are methods of using compounds of formula (IA, IB, IIA, IIB, IIIA, IIIB) that are aryl- and heteroaryl-substituted tetrahydroisoquinolines, for the treatment of chronic and neuropathic pain, the treatment and prevention of migraine headache, and the treatment of stress, urge and mixed urinary incontinence. L'invention concerne des méthodes d'utilisation de composés de formule (IA, IB, IIA, IIB, IIIA, IIIB) qui sont des tétrahydroisoquinolines à substitution aryle et hétéroaryle, pour le traitement de la douleur chronique et neuropathique, pour le traitement et la prévention de la migraine, ainsi que pour le traitement du stress, de l'incontinence urinaire impérieuse et mixte.