CSNKS AS MODIFIERS OF THE RAC PATHWAY AND METHODS OF USE

Human CSNK genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of CSNK are provided. Selon l'invention,...

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Bibliographische Detailangaben
Hauptverfasser:	FRANCIS, GEORGE, ROSS, BJERKE, LYNN, MARGARET, KADYK, LISA, C
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Human CSNK genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of CSNK are provided. Selon l'invention, des gènes humains de caséine kinase (CSNK) ont été identifiés comme étant des modulateurs de la voie RAC et constituent par conséquent des cibles pour des troubles associés à un dysfonctionnement de RAC. L'invention concerne des procédés pour identifier des modulateurs de RAC, consistant à cribler des agents qui modulent l'activité de CSNK.