PYRAZINE COMPOUNDS AS CRF MODULATORS

PYRAZINE COMPOUNDS AS CRF MODULATORS

Disclosed are pyrazine derivatives, pharmaceutical compositions containing them, and methods of using them to treat a disorder or condition the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as an anxiety-related disorder or affective disorder. Cette invention...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: MICKELSON, JOHN, WARREN
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed are pyrazine derivatives, pharmaceutical compositions containing them, and methods of using them to treat a disorder or condition the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as an anxiety-related disorder or affective disorder. Cette invention concerne des dérivés de pyrazine, des compositions pharmaceutiques renfermant ces dérivés et des méthodes d'utilisation desdits dérivés pour le traitement d'une manifestation pathologique ou d'une maladie, relevant de l'angoisse ou d'un trouble émotionnel par exemple, au moyen d'un antagoniste du récepteur du facteur de libération de la corticotropine (CRF).