ANTIINFLAMMATION AGENTS

Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic, infectious and cell proliferative diseases or conditions are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins i...

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Bibliographische Detailangaben
Hauptverfasser:	LIVELY, SARAH, E, CUSHING, TIMOTHY, D, JIAO, XIAN, YUN, LABELLE, MARC, SMITH, ANDREW, DEGRAFFENREID, MICHAEL, R, SMITH, MARIE-LOUISE, RASMUSSEN, SVEN, P, FARTHING, CHRISTOPHER, N, HAO, XIAOLIN, KOPECKY, DAVID, J, SHIN, YOUNGSOOK, CARDOZO, MARIO, G, MCMINN, DUSTIN, L, BURKITT, SIMON, A, JAEN, JUAN, C
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic, infectious and cell proliferative diseases or conditions are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism, infection and cell proliferation. The subject compounds contain a fused heterobicyclic ring. L'invention concerne des composés, des compositions et des méthodes utilisés dans le traitement de maladies ou d'états pathologiques inflammatoires, immuno-régulateurs, métaboliques, infectieux et à prolifération cellulaire. L'invention concerne en particulier des composés modulant l'expression et/ou la fonction des protéines associées à l'inflammation, le métabolisme, l'infection et la prolifération cellulaire. Les composés de l'invention contiennent un noyau hétérobicyclique accolé.