SUBSTITUTED PEPTIDES USEFUL IN THE TREATMENT OF ALZHEIMER'S DISEASE

Disclosed are methods for treating Alzheimer's disease, and other diseases, and/or inhibiting beta-secretase enzyme, and/or inhibiting deposition of A beta peptide in a mammal, by use of compounds of formula (I), wherein Ar, W, Z, Q, R1, U, and L, are as herein defined. L'invention concern...

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1. Verfasser: BECK, JAMES, T
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Disclosed are methods for treating Alzheimer's disease, and other diseases, and/or inhibiting beta-secretase enzyme, and/or inhibiting deposition of A beta peptide in a mammal, by use of compounds of formula (I), wherein Ar, W, Z, Q, R1, U, and L, are as herein defined. L'invention concerne des méthodes permettant de traiter la maladie d'Alzheimer, et d'autres maladies, et/ou d'inhiber l'enzyme bêta-sécrétase, et/ou d'inhiber le dépôt de peptide bêta A chez un mammifère, par utilisation de composés de formule (I), dans laquelle Ar, W, Z, Q, R1, U et L sont tels que définis dans la description.