USE OF GUANOSINE OR INOSINE AS ANTI-APOPTOTIC AGENTS IN THE TREATMENT OF I. A. NEURODEGENERATIVE DISEASES OR INJURIES AT THE NERVOUS SYSTEM

Methods and compositions for preventing apoptosis are described. The method involves administering an effective amount of a purine nucleoside to a cell or an animal in need thereof. The methods are useful in treating diseases of the nervous system including neurodegenerative diseases, stroke or spin...

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Hauptverfasser:	CACIAGLI, FRANCESCO, WERSTIUK, EVA, SUSANNE, VERTES, EVA, CICCARELLI, RENATA, DI IORIO, PATRIZIA, KLEYWEGT, SONYA, RATHBONE, MICHEL, P
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Methods and compositions for preventing apoptosis are described. The method involves administering an effective amount of a purine nucleoside to a cell or an animal in need thereof. The methods are useful in treating diseases of the nervous system including neurodegenerative diseases, stroke or spinal cord injuries. L'invention concerne des procédés et des compositions destinés à prévenir l'apoptose. Ce procédé consiste à administrer une quantité efficace d'un nucléoside de purine à une cellule ou à un animal qui en a besoin. Ces procédés sont utiles dans le traitement de maladies du système nerveux telles que les maladies neurodégénératives, l'accident vasculaire cérébral ou les traumatismes médullaires.