REGULATION OF THE GROWTH HORMONE/IGF-1 AXIS

This disclosure provides, inter alia, treatments and compositions that alter life span regulation and cellular responses to diseases and disorders by antagonizing the GH/1IGF-1 axis. Also provided are methods of screening for agents that can modulate the GH/IGF-1 axis. L'invention concerne, ent...

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Bibliographische Detailangaben
Hauptverfasser: BAYLEY, CYNTHIA, A, CANNON, L., EDWARD, DISTEFANO, PETER
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:This disclosure provides, inter alia, treatments and compositions that alter life span regulation and cellular responses to diseases and disorders by antagonizing the GH/1IGF-1 axis. Also provided are methods of screening for agents that can modulate the GH/IGF-1 axis. L'invention concerne, entre autres, des traitements et des compositions permettant de modifier la régulation de la durée de vie et les réponses cellulaires à des maladies et des troubles par antagonisation de l'axe GH/IGF-1. L'invention concerne également des méthodes de criblage d'agents pouvant moduler l'axe GH/IGF-1.