DIHYDROPYRIDINE DERIVATIVES FOR USE AS HUMAN NEUTROPHIL ELASTASE INHIBITORS

The invention relates to novel dihydropyridine derivatives, of Formula (I) processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development. L'...

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Hauptverfasser: BAERFACKER, LARS, MEURER, DIRK, ALLERHEILIGEN, SVEN, NASH, KEVIN, MIN-JIAN LI, VOLKHART, ALBRECHT, BARBARA, SCHLEMMER, KARL-HEINZ, ROSENTRETER, ULRICH, FITZGERALD, MARY, F, GIELEN, HEIKE, TELAN, LEILA, KELDENICH, JOERG
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to novel dihydropyridine derivatives, of Formula (I) processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development. L'invention concerne des nouveaux dérivés de dihydropyridine de formule (I), leurs procédés de préparation et leur utilisation dans des médicaments, notamment pour le traitement de bronchopneumopathies obstructives, du syndrome coronarien aigu, de l'infarctus aigu du myocarde et du développement d'une insuffisance cardiaque.