NOVEL DEOXYURIDINE 5'TRIPHOSPHATE NUCLEOTIDOHYDROLASE POLYPEPTIDES AND STRUCTURES

The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified proteins comprising the amino acid sequences set forth in SEQ ID NO: 4 and SEQ ID NO: 13. The invention also provides biochemical and biophysical characteristics of the polypepti...

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Bibliographische Detailangaben
Hauptverfasser: VEDADI, MASOUD, AWREY, DONALD, DOMAGALA, MEGAN, KIMBER, MATTHEW, DHARAMSI, AKIL, EDWARDS, ALED, BEATTIE, BRYAN, HOUSTON, SIMON, MANSOURY, KAMRAN
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to novel drug targets for pathogenic bacteria. Accordingly, the invention provides purified proteins comprising the amino acid sequences set forth in SEQ ID NO: 4 and SEQ ID NO: 13. The invention also provides biochemical and biophysical characteristics of the polypeptides of the invention. L'invention concerne des cibles de médicament pour des bactéries pathogènes. Elle concerne, en conséquence, des protéines purifiées dont les séquences en acides aminés sont représentées dans SEQ ID NO: 4 et SEQ ID NO: 13. Elle concerne aussi des caractéristiques biochimiques et biophysiques de ces polypeptides.