APPARATUS AND METHOD FOR THE PURIFICATION OF NUCLEIC ACIDS

The present invention is directed to novel device comprising a sol-gel filled microchannel and methods for purifying nucleic acids from biological samples. In one embodiment shown in figure 1, the microfluidic device (1) comprises a base (2) with a microchannel (3) formed in the interior of base (2)...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	NORRIS, PAMELA, M, WOLFE, KELLEY, A, POWER, MARY, E, BREADMORE, MICHAEL, C, SHRINIVASAN, SUSHIL, LANDERS, JAMES, P, FERRANCE, JEROME, P
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION TECHNICAL SUBJECTS COVERED BY FORMER USPC TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TESTING THEIR RELEVANT APPARATUS TRANSPORTING VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention is directed to novel device comprising a sol-gel filled microchannel and methods for purifying nucleic acids from biological samples. In one embodiment shown in figure 1, the microfluidic device (1) comprises a base (2) with a microchannel (3) formed in the interior of base (2), wherein said microchannel (3) is filled with a sol-gel matrix and in fluid communication with an inlet port (4) and outlet port (5) wherein inlet port (4) and outlet port (5) are formed on the exterior surface (10) of base (2). The device may be further provided with additional components to allow for analytical analysis of the purified nucleic acid sequences. L'invention concerne un nouveau dispositif comprenant un microcanal rempli d'un sol-gel, et des procédés de purification d'acides nucléiques provenant d'échantillons biologiques. Dans un mode de réalisation illustré dans la figure, un dispositif microfluidique (1) comprend une base (2) à l'intérieur de laquelle est formé un microcanal (3), celui-ci étant rempli d'une matrice sol-gel et étant en communication fluidique avec un orifice d'entrée (4) et un orifice de sortie (5), ceux-ci étant formés sur la surface extérieure (10) de la base (2). Ce dispositif peut en outre être doté de composants supplémentaires pour permettre une analyse analytique des séquences d'acides nucléiques purifiés.