METHOD OF SELECTING TARGETS FOR GENE SILENCING BY RNA INTERFERENCE
The invention relates to the selection of target regions of RNA transcripts for specific down-regulation of gene expression by RNA interference. Target regions of the transcript are identified on the basis of hybridisation to scanning arrays of antisense oligonucleotides and siRNA reagents comprisin...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | SOHAIL, MUHAMMAD MACAULAY, VALENTINE, MOYA |
| description | The invention relates to the selection of target regions of RNA transcripts for specific down-regulation of gene expression by RNA interference. Target regions of the transcript are identified on the basis of hybridisation to scanning arrays of antisense oligonucleotides and siRNA reagents comprising double-stranded RNAs corresponding to the target regions are then synthesised.
L'invention concerne la sélection de régions cibles de transcripts d'ARN pour la régulation descendante spécifique de l'expression génique par interférence d'ARN. Des régions cibles du transcript sont identifiées sur la base de l'hybridation sur réseaux scanneurs d'oligonucléotides anti-sens, et des réactifs ARNsi comprenant des ARN à double brin correspondant aux régions cibles sont alors synthétisés. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO03100093A2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO03100093A2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO03100093A23</originalsourceid><addsrcrecordid>eNrjZHDydQ3x8HdR8HdTCHb1cXUO8fRzVwhxDHJ3DQlWcPMPUnB39XNVCPb0cfVzBkk5RSoE-TkqePqFuAa5uQYBRV15GFjTEnOKU3mhNDeDoptriLOHbmpBfnxqcUFicmpeakl8uL-BsaGBgYGlsaORMTFqAOJKKv0</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>METHOD OF SELECTING TARGETS FOR GENE SILENCING BY RNA INTERFERENCE</title><source>esp@cenet</source><creator>SOHAIL, MUHAMMAD ; MACAULAY, VALENTINE, MOYA</creator><creatorcontrib>SOHAIL, MUHAMMAD ; MACAULAY, VALENTINE, MOYA</creatorcontrib><description>The invention relates to the selection of target regions of RNA transcripts for specific down-regulation of gene expression by RNA interference. Target regions of the transcript are identified on the basis of hybridisation to scanning arrays of antisense oligonucleotides and siRNA reagents comprising double-stranded RNAs corresponding to the target regions are then synthesised.
L'invention concerne la sélection de régions cibles de transcripts d'ARN pour la régulation descendante spécifique de l'expression génique par interférence d'ARN. Des régions cibles du transcript sont identifiées sur la base de l'hybridation sur réseaux scanneurs d'oligonucléotides anti-sens, et des réactifs ARNsi comprenant des ARN à double brin correspondant aux régions cibles sont alors synthétisés.</description><edition>7</edition><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2003</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20031204&DB=EPODOC&CC=WO&NR=03100093A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20031204&DB=EPODOC&CC=WO&NR=03100093A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SOHAIL, MUHAMMAD</creatorcontrib><creatorcontrib>MACAULAY, VALENTINE, MOYA</creatorcontrib><title>METHOD OF SELECTING TARGETS FOR GENE SILENCING BY RNA INTERFERENCE</title><description>The invention relates to the selection of target regions of RNA transcripts for specific down-regulation of gene expression by RNA interference. Target regions of the transcript are identified on the basis of hybridisation to scanning arrays of antisense oligonucleotides and siRNA reagents comprising double-stranded RNAs corresponding to the target regions are then synthesised.
L'invention concerne la sélection de régions cibles de transcripts d'ARN pour la régulation descendante spécifique de l'expression génique par interférence d'ARN. Des régions cibles du transcript sont identifiées sur la base de l'hybridation sur réseaux scanneurs d'oligonucléotides anti-sens, et des réactifs ARNsi comprenant des ARN à double brin correspondant aux régions cibles sont alors synthétisés.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2003</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHDydQ3x8HdR8HdTCHb1cXUO8fRzVwhxDHJ3DQlWcPMPUnB39XNVCPb0cfVzBkk5RSoE-TkqePqFuAa5uQYBRV15GFjTEnOKU3mhNDeDoptriLOHbmpBfnxqcUFicmpeakl8uL-BsaGBgYGlsaORMTFqAOJKKv0</recordid><startdate>20031204</startdate><enddate>20031204</enddate><creator>SOHAIL, MUHAMMAD</creator><creator>MACAULAY, VALENTINE, MOYA</creator><scope>EVB</scope></search><sort><creationdate>20031204</creationdate><title>METHOD OF SELECTING TARGETS FOR GENE SILENCING BY RNA INTERFERENCE</title><author>SOHAIL, MUHAMMAD ; MACAULAY, VALENTINE, MOYA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO03100093A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2003</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>SOHAIL, MUHAMMAD</creatorcontrib><creatorcontrib>MACAULAY, VALENTINE, MOYA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SOHAIL, MUHAMMAD</au><au>MACAULAY, VALENTINE, MOYA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD OF SELECTING TARGETS FOR GENE SILENCING BY RNA INTERFERENCE</title><date>2003-12-04</date><risdate>2003</risdate><abstract>The invention relates to the selection of target regions of RNA transcripts for specific down-regulation of gene expression by RNA interference. Target regions of the transcript are identified on the basis of hybridisation to scanning arrays of antisense oligonucleotides and siRNA reagents comprising double-stranded RNAs corresponding to the target regions are then synthesised.
L'invention concerne la sélection de régions cibles de transcripts d'ARN pour la régulation descendante spécifique de l'expression génique par interférence d'ARN. Des régions cibles du transcript sont identifiées sur la base de l'hybridation sur réseaux scanneurs d'oligonucléotides anti-sens, et des réactifs ARNsi comprenant des ARN à double brin correspondant aux régions cibles sont alors synthétisés.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO03100093A2 |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | METHOD OF SELECTING TARGETS FOR GENE SILENCING BY RNA INTERFERENCE |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T17%3A55%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=SOHAIL,%20MUHAMMAD&rft.date=2003-12-04&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO03100093A2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |