DERIVATIVES OF HYDROXYPHENYL, A METHOD FOR PREPARING THEREOF AND THEIR PHARMACEUTICAL COMPOSITION
The present invention relates to derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition, more particularly the compounds of the present invention specifically inhibit the activation of T lymphocyte by src homology region 2(SH2) domain of T lymphocyte (lck),...
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| creator | KIM, SUNG-JOO YOUN, JEEHEE YUN, YUNGDAE LEE, KEUNHYEUNG PARK, SEEHYOUNG OH, JAETAEK HUR, YUN-GYOUNG WON, JONGWHA KANG, MI-AE PARK, DOOHONG YUN, SU-YOUNG |
| description | The present invention relates to derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition, more particularly the compounds of the present invention specifically inhibit the activation of T lymphocyte by src homology region 2(SH2) domain of T lymphocyte (lck), so that they can be used for the treatment, prevention and/or diagnosis of graft rejection, autoimmune diseases, inflammatory diseases, etc.
La présente invention concerne des dérivés d'hydroxyphényle, leur méthode de préparation et leur composition pharmaceutique. Plus particulièrement, les composés de la présente invention inhibent spécifiquement l'activation des lymphocytes T par le domaine de région 2 à homologie Src (SH2) du lymphocyte T (lck), de sorte qu'ils peuvent être utilisés pour le traitement, la prévention et/ou le diagnostic du rejet de greffe, de maladies auto-immunes, de maladies inflammatoires, etc. |
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La présente invention concerne des dérivés d'hydroxyphényle, leur méthode de préparation et leur composition pharmaceutique. Plus particulièrement, les composés de la présente invention inhibent spécifiquement l'activation des lymphocytes T par le domaine de région 2 à homologie Src (SH2) du lymphocyte T (lck), de sorte qu'ils peuvent être utilisés pour le traitement, la prévention et/ou le diagnostic du rejet de greffe, de maladies auto-immunes, de maladies inflammatoires, etc.</description><edition>7</edition><language>eng ; fre</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2003</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20031030&DB=EPODOC&CC=WO&NR=03089405A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20031030&DB=EPODOC&CC=WO&NR=03089405A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KIM, SUNG-JOO</creatorcontrib><creatorcontrib>YOUN, JEEHEE</creatorcontrib><creatorcontrib>YUN, YUNGDAE</creatorcontrib><creatorcontrib>LEE, KEUNHYEUNG</creatorcontrib><creatorcontrib>PARK, SEEHYOUNG</creatorcontrib><creatorcontrib>OH, JAETAEK</creatorcontrib><creatorcontrib>HUR, YUN-GYOUNG</creatorcontrib><creatorcontrib>WON, JONGWHA</creatorcontrib><creatorcontrib>KANG, MI-AE</creatorcontrib><creatorcontrib>PARK, DOOHONG</creatorcontrib><creatorcontrib>YUN, SU-YOUNG</creatorcontrib><title>DERIVATIVES OF HYDROXYPHENYL, A METHOD FOR PREPARING THEREOF AND THEIR PHARMACEUTICAL COMPOSITION</title><description>The present invention relates to derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition, more particularly the compounds of the present invention specifically inhibit the activation of T lymphocyte by src homology region 2(SH2) domain of T lymphocyte (lck), so that they can be used for the treatment, prevention and/or diagnosis of graft rejection, autoimmune diseases, inflammatory diseases, etc.
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La présente invention concerne des dérivés d'hydroxyphényle, leur méthode de préparation et leur composition pharmaceutique. Plus particulièrement, les composés de la présente invention inhibent spécifiquement l'activation des lymphocytes T par le domaine de région 2 à homologie Src (SH2) du lymphocyte T (lck), de sorte qu'ils peuvent être utilisés pour le traitement, la prévention et/ou le diagnostic du rejet de greffe, de maladies auto-immunes, de maladies inflammatoires, etc.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | DERIVATIVES OF HYDROXYPHENYL, A METHOD FOR PREPARING THEREOF AND THEIR PHARMACEUTICAL COMPOSITION |
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