DERIVATIVES OF HYDROXYPHENYL, A METHOD FOR PREPARING THEREOF AND THEIR PHARMACEUTICAL COMPOSITION

The present invention relates to derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition, more particularly the compounds of the present invention specifically inhibit the activation of T lymphocyte by src homology region 2(SH2) domain of T lymphocyte (lck),...

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Bibliographische Detailangaben
Hauptverfasser:	KIM, SUNG-JOO, YOUN, JEEHEE, YUN, YUNGDAE, LEE, KEUNHYEUNG, PARK, SEEHYOUNG, OH, JAETAEK, HUR, YUN-GYOUNG, WON, JONGWHA, KANG, MI-AE, PARK, DOOHONG, YUN, SU-YOUNG
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition, more particularly the compounds of the present invention specifically inhibit the activation of T lymphocyte by src homology region 2(SH2) domain of T lymphocyte (lck), so that they can be used for the treatment, prevention and/or diagnosis of graft rejection, autoimmune diseases, inflammatory diseases, etc. La présente invention concerne des dérivés d'hydroxyphényle, leur méthode de préparation et leur composition pharmaceutique. Plus particulièrement, les composés de la présente invention inhibent spécifiquement l'activation des lymphocytes T par le domaine de région 2 à homologie Src (SH2) du lymphocyte T (lck), de sorte qu'ils peuvent être utilisés pour le traitement, la prévention et/ou le diagnostic du rejet de greffe, de maladies auto-immunes, de maladies inflammatoires, etc.