NOVEL THYROID RECEPTOR LIGANDS

This invention relates to novel compounds according to the general formula : which are thyroid receptor ligands, preferably antagonists, partial antagonists or partial agonists and to methods for using such compounds in the treatment of cardiac and metabolic disorders, such as cardiac arrhythmias, t...

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Bibliographische Detailangaben
Hauptverfasser:	MALM, JOHAN, RAHIMI-GHADIM, MAHMOUD, GARG, NEERAJ
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to novel compounds according to the general formula : which are thyroid receptor ligands, preferably antagonists, partial antagonists or partial agonists and to methods for using such compounds in the treatment of cardiac and metabolic disorders, such as cardiac arrhythmias, thyro-toxicosis, subclinical hyperthyrodism and liver diseases. La présente invention concerne de nouveaux composés de formule générale : ( ) qui sont des ligands de récepteurs thyroïdiens, de préférence des antagonistes, des antagonistes partiels ou des agonistes partiels ainsi que des méthodes d'utilisation desdits composés dans le traitement de troubles cardiaques et métaboliques, tels que les arrythmies cardiaques, la thyrotoxicose, l'hyperthyroïdie infraclinique et les maladies hépatiques.