METHOD AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF NON-SMALL CELL LUNG CANCER USING GENE EXPRESSION PROFILES

The present invention identifies and quantifies changes in gene expression associated with non-small cell lung cancer NSCLC by examining gene expression in tissue from normal lung and diseased lung. The present invention also identifies and quantifies expression profiles which serve as useful diagno...

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Hauptverfasser:	WEAVER, DAVID, A, CRAWFORD, ERIN, L, WARNER, KRISTY, A, DEMUTH, JEFFREY, P, WILLEY, JAMES, C, GRAVES, TIMOTHY, G
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Zusammenfassung:	The present invention identifies and quantifies changes in gene expression associated with non-small cell lung cancer NSCLC by examining gene expression in tissue from normal lung and diseased lung. The present invention also identifies and quantifies expression profiles which serve as useful diagnostic markers as well as markers that are useful to monitor disease states, disease progression, drug toxicity, drug efficacy and drug metabolism. L'invention concerne l'identification et la quantification des changements au niveau de l'expression génique associée au cancer bronchopulmonaire "non à petites cellules" (NSCLC) par examen de l'expression génique des tissus d'un poumon normal et d'un poumon malade. L'invention concerne également l'identification et la quantification des profils d'expression servant de marqueurs de diagnostic utiles et de marqueurs permettant de surveiller des états pathologiques, la progression de la maladie, la toxicité des médicaments, leur efficacité et leur métabolisme.