A PROCESS FOR THE PREPARATION OF CEPHALOSPORAN ACID DERIVATIVES FROM CEPHALOSPORIN C

A process for the preparation of cephalosporin acid derivatives comprises the step of enzymatically converting cephalosporin C into 7 cephalosporin acid derivatives in the presence of two biocatalysts, wherein one biocatalyst comprises co-immobilised D-amino acid oxidase and a catalase enzyme, and t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	GUISAN SEIJAS, JOSE M, HUERTAS HIDALGO, AURELIO, FERNANDEZ LAFUENTE, ROBERTO, FERNANDEZ LORENTE, GLORIA, BETANCORT, LORENA DUTRENIT, GONZALEZ MATEO, CESAR
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A process for the preparation of cephalosporin acid derivatives comprises the step of enzymatically converting cephalosporin C into 7 cephalosporin acid derivatives in the presence of two biocatalysts, wherein one biocatalyst comprises co-immobilised D-amino acid oxidase and a catalase enzyme, and the other biocatalyst comprises immobilised glutaryl acylase. L'invention concerne un procédé de préparation de dérivés acides de céphalosporine comprenant l'étape de conversion enzymatique de céphalosporine C en dérivés acides de céphalosporine 7 en présence de deux biocatalyseurs, un biocatalyseur comprenant une D-aminoacide-oxydase co-immobilisée et une enzyme catalase, et l'autre biocatalyseur comprenant une glutaryl-acylase immobilisée.