METHODS AND COMPOSITIONS FOR TREATING AIDS AND HIV-RELATED DISORDERS USING 1414, 1481, 1553, 34021, 1720, 1683, 1552, 1682, 1675, 12825, 9952, 5816, 10002, 1611, 1371, 14324, 126, 270, 312, 167, 326, 18926, 6747, 1793, 1784, OR 2045 MOLECULES

The present invention relates to methods for diagnosis and treatment of AIDS or an HIV-related disorder or disorders. Specifically, the present invention identifies the differential expression of 1414, 1481, 1553, 34021, 1720, 1683, 1552, 1682, 1675, 12825, 9952, 5816, 10002, 1611, 1371, 14324, 126,...

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Bibliographische Detailangaben
Hauptverfasser:	POWELL, DOUGLAS M, WEICH, NADINE S
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to methods for diagnosis and treatment of AIDS or an HIV-related disorder or disorders. Specifically, the present invention identifies the differential expression of 1414, 1481, 1553, 34021, 1720, 1683, 1552, 1682, 1675, 12825, 9952, 5816, 10002, 1611, 1371, 14324, 126, 270, 312, 167, 326, 18926, 6747, 1793, 1784, and 2045 genes in tissues relating to AIDS or an HIV-related disorder, relative to their expression in normal, or non-AIDS or HIV-related disease states, and/or in response to manipulations relevant to AIDS or an HIV-related disorder. The present invention describes methods for the diagnostic evaluation and prognosis of various HIV-related disorders, and for the identification of subjects exhibiting a predisposition to such conditions. The invention also provides methods for identifying a compound capable of modulating AIDS or an HIV-related disorder or disorders. The present invention also provides methods for the ident ification and therapeutic use of compounds as treatments of AIDS or an HIV-related disorder. L'invention concerne des méthodes pour le diagnostic et pour le traitement du SIDA ou d'un trouble ou de plusieurs troubles associés au VIH. En particulier, l'invention permet d'identifier l'expression différentielle de gènes 1414, 1481, 1553, 34021, 1720, 1683, 1552, 1682, 1675, 12825, 9952, 5816, 10002, 1611, 1371, 14324, 126, 270, 312, 167, 326, 18926, 6747, 1793, 1784 et 2045, dans des tissus associés au SIDA ou à un trouble associé au VIH, et leur expression dans des états pathologiques normaux, ou non associés au SIDA ou au VIH, et/ou en réponse à des manipulations concernant le SIDA ou un trouble associé au VIH. L'invention concerne des méthodes pour l'évaluation diagnostique et le pronostic de troubles variés associés au VIH et pour l'identification de sujets présentant une prédisposition à de tels états. L'invention concerne des méthodes d'identification d'un composé pouvant moduler le SIDA ou un trouble ou plusieurs troubles associés au VIH. L'invention concerne également des méthodes d'identification et d'utilisation thérapeutique de composés en tant que traitements du SIDA ou d'un trouble associé au VIH.