NON-PEPTIDE COMPOUNDS AFFECTING THE ACTION OF GONADOTROPIN-RELEASING HORMONE (GNRH)

Non-peptide GnRH agents that inhibit the effect of gonadotropin-releasing hormone are described. Such agents are useful for treating mammalian reproductive disorders and steroid hormone-dependent tumors as well as for regulating fertility, where suppression of gonadotropin release is indicated. The...

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Bibliographische Detailangaben
Hauptverfasser:	TOMPKINS, EILEEN, VALENZUELA, HONG, YUFENG, VAZIR, HARESH, NARENDRA, CHRISTIE, LANCE, CHRISTOPHER, PATHAK, VED, PRAKASH, FENG, JUN, LI, HAITAO, RAJAPAKSE, RANJAN, JAGATH, ANDERSON, MARK, BRIAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Non-peptide GnRH agents that inhibit the effect of gonadotropin-releasing hormone are described. Such agents are useful for treating mammalian reproductive disorders and steroid hormone-dependent tumors as well as for regulating fertility, where suppression of gonadotropin release is indicated. The compound have the following structure: (Formula I) L'invention porte sur des agents non-peptidiques inhibant les effets gonadolibérine (GnRH). Lesdits agents servent à traiter les troubles de reproduction des mammifères et les tumeurs liées aux hormones stéroïdiennes, et à réguler la fécondité lorsque la suppression de ladite hormone est indiquée. Ledit composé présente la structure suivante.