STRUCTURAL BASIS OF QUORUM SENSING SIGNAL GENERATION AND METHODS AND THERAPEUTIC AGENTS DERIVED THEREFROM

The three dimensional structure of acyl-homoserine lactone synthases, and particularly Esal and Lasl, and uses thereof. Novel acyl-homoserie lactone synthases from mycobacteria, nuclei acid molecules encoding such synthases, recombinant molecules and host cells, and uses thereof. L'invention co...

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Hauptverfasser:	VON BODMAN, SUSANNE, B, WATSON, WILLIAM, T, GOULD, TY, A, HOANG, TUNG, THANH, CHURCHILL, MAIR, E., A, MURHPY, IV, FRANK, V, SCHWEIZER, HERBERT, P
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The three dimensional structure of acyl-homoserine lactone synthases, and particularly Esal and Lasl, and uses thereof. Novel acyl-homoserie lactone synthases from mycobacteria, nuclei acid molecules encoding such synthases, recombinant molecules and host cells, and uses thereof. L'invention concerne une structure tridimensionnelle de synthases d'acyl-homosérine lactone, et notamment Esal et Lasl, ainsi que des utilisations correspondantes. Elle concerne également des nouvelles synthases d'acyl-homosérine lactone issues de mycobactéries, des molécules d'acides nucléiques codant pour ces synthases, des molécules recombinantes et des cellules hôtes, ainsi que leurs utilisations.