MOLECULES FOR DISEASE DETECTION AND TREATMENT

The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The inv...

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Hauptverfasser:	LEWIS, SAMANTHA, A, DAM, TAM, C, CHINN, JOYCE, GIETZEN, DARRYL, DAHL, CHRISTOPHER, R, AMSHEY, STEFAN, R, CHEN, ALICE, J, KOLLURU, VIJAYKUMAR, TUASON, OLIVIA, MARWAHA, RAKESH, URASHKA, MICHAEL, E, LAN, RUTH, Y, KRISTNAM, SREENIVASA, R, PERALTA, CAREYNA, H, YAP, PIERRE, E, PANESAR, IQBAL, S, DUFOUR, GERARD, E, LIU, TOMMY, F, JONES, ANISSA, L, JACKSON, JENNIFER, L, YU, JIMMY, Y, GERSTIN, EDWARD, H., JR
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing mddt for the expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce antibodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use. La présente invention concerne des polynucléotides purifiés de molécules pour la détection et le traitement de maladies (mddt). L'invention concerne également les polypeptides (MDDT) codés par les mddt. L'invention concerne en outre l'utilisation de mddt, ou de compléments, d'oligonucléotides ou de fragments de ceux-ci dans des analyses diagnostiques. L'invention concerne également des vecteurs et des cellules hôtes contenant des mddt pour l'expression des MDDT. Par ailleurs, l'invention concerne l'utilisation de MDDT isolés et purifiés pour induire des anticorps et cribler des bibliothèques de composés ainsi que l'utilisation d'anticorps anti-MDDT dans des analyses diagnostiques. L'invention concerne enfin des microréseaux contenant des mddt et des méthodes d'utilisation.