ANTISENSE MODULATION OF NOD1 EXPRESSION

Antisense compounds, compositions and methods are provided for modulating the expression of NOD1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding NOD1. Methods of using these compounds for modulation of NOD1 expression and fo...

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Bibliographische Detailangaben
Hauptverfasser: ROACH, MARK, P, DOBIE, KENNETH, W
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Antisense compounds, compositions and methods are provided for modulating the expression of NOD1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding NOD1. Methods of using these compounds for modulation of NOD1 expression and for treatment of diseases associated with expression of NOD1 are provided. L'invention concerne des composés antisens, des compositions et des procédés permettant de moduler l'expression de NOD1. Les compositions comprennent des composés antisens, en particulier, des oligonucléotides antisens, ciblés sur des acides nucléiques codant NOD1. L'invention traite de procédés d'utilisation de ces composés pour moduler l'expression de NOD1 et pour traiter les maladies associées à l'expression de NOD1.