BENZIMIDAZOLES USEFUL AS PROTEIN KINASE INHIBITORS

Disclosed are substituted benzimidazole compounds of formula (I) wherein R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention are useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are pr...

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Bibliographische Detailangaben
Hauptverfasser:	SARKO, CHRISTOPHER, RONALD, WILSON, NOEL, STEWART, PULLEN, STEVEN, S, SNOW, ROGER, JOHN, LEE, JINBO, CYWIN, CHARLES, ROTH, GREGORY, PAUL
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed are substituted benzimidazole compounds of formula (I) wherein R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention are useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds. L'invention concerne des composés de benzimidazole substitués de formule (I), dans laquelle R1, R2, R3, R4 et Xa sont définis. On utilise les composés de cette invention pour traiter des maladies et des conditions pathologiques impliquant des inflammations, des troubles immunologiques et allergiques. Cette invention a également trait à des processus de préparation de ces composés et à des compositions pharmaceutiques contenant ces composés.