PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS

This invention is directed to compounds of the formula (I) to N-oxides, prodrugs, acid bioisosteres, pharmaceutically acceptable salts or solvates of such compounds, or N-oxides, prodrugs, or acid bioisosteres of such salts or solvates, to compositions comprising such compounds, and to methods of tr...

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Bibliographische Detailangaben
Hauptverfasser:	MCLAY, LAIN, MCFARLANE, ALDOUS, DAVIS, JOHN, AMENDOLA, SHELLEY, MAJID, TAHIR, NADEEM, DEPRETS, STEPHANIE, DANIELE, COX, PAUL, JOSEPH, EDLIN, CHRIS, HALLEY, FRANK, BAUDOIN, BERNARD, EDWARDS, MICHAEL, PEDGRIFT, BRIAN, LESLIE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention is directed to compounds of the formula (I) to N-oxides, prodrugs, acid bioisosteres, pharmaceutically acceptable salts or solvates of such compounds, or N-oxides, prodrugs, or acid bioisosteres of such salts or solvates, to compositions comprising such compounds, and to methods of treatment comprising administering, to a patient in need thereof, such compounds and compositions. La présente invention se rapporte à des composés représentés par la formule (I) ainsi qu'à des N-oxydes, des promédicaments, des bioisostères acides, des sels ou solvates pharmaceutiquement acceptables de ces composés, ou des N-oxydes, des promédicaments ou des bioisostères acides de ces sels ou solvates. L'invention se rapporte également à des compositions contenant ces composés ainsi qu'à des procédés de traitement consistant à administrer, à un patient justiciable d'un tel traitement, ces composés et compositions.