SUBSTITUTED INDOLES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH INDOLES AND THEIR USE AS PPAR- gamma BINDING AGENTS

Disclosed are substituted indoles, pharmaceutical compositions containing such indoles, and their use in treating or preventing PPAR- gamma mediated diseases or conditions, such as osteopenia, osteoporosis, cancer, diabetes and atherosclerosis. Cette invention se rapporte à des indoles substituées,...

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Hauptverfasser:	BULLOCK, WILLIAM, H, NAGARATHNAM, DHANAPALAN, CAMPBELL, ANN-MARIE, STOLLE, ANDREAS, SU, NING, DUMAS, JACQUES, P, MAGNUSON, STEVEN, R, WANG, YAMIN, BARYZA, JEREMY, L, COOK, JAMES, H, CARLEY, WILLIAM, QI, NING, COISH, PHILLIP, D., G, LOWE, DEREK, B
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed are substituted indoles, pharmaceutical compositions containing such indoles, and their use in treating or preventing PPAR- gamma mediated diseases or conditions, such as osteopenia, osteoporosis, cancer, diabetes and atherosclerosis. Cette invention se rapporte à des indoles substituées, à des compositions pharmaceutiques contenant ces indoles et à leur utilisation pour traiter ou prévenir les affections ou les états à médiation par PPAR- gamma , tels que l'ostéopénie, l'ostéoporose, le cancer, le diabète et l'athérosclérose.