GENETICALLY ENGINEERED CO-EXPRESSION DNA VACCINES, CONSTRUCTION METHODS AND USES THEREOF

The present invention relates to co-expression DNA vaccines and methods for vaccinating animals against viral, bacterial and parasitic pathogens. In particular, the present invention relates to DNA vaccines that co-express antigens in combination with biologically-active components, such as adjuvant...

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Bibliographische Detailangaben
Hauptverfasser: AGWALE, SIMON, LEWIS, GEORGE, OBRIECHT, CHRISTINE, SHATA, MT, HONE, DAVID, FOUTS, TIMOTHY, BAGLEY, KEN, BOYSON, MICHAEL
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to co-expression DNA vaccines and methods for vaccinating animals against viral, bacterial and parasitic pathogens. In particular, the present invention relates to DNA vaccines that co-express antigens in combination with biologically-active components, such as adjuvants, immunoregulatory agents, antisense RNAs, and/or catalytic RNAs. L'invention concerne des vaccins à base d'ADN à co-expression et des procédés pour la vaccination d'animaux contre des agents pathogènes viraux, bactériens et parasites. L'invention concerne notamment des vaccins à base d'ADN qui co-expriment des antigènes en combinaison avec des composants actifs biologiquement, tels que des adjuvants, des agents immunorégulateurs, des ARN antisens ou des ARN catalytiques.