IDENTIFICATION OF NEW THERAPEUTIC TARGETS FOR MODULATING BILE ACID SYNTHESIS

Methods for identifying compounds that modulate bile acid synthesis by assessing their ability to act as ligands for short heterodimerizing partner-1 or liver receptor homologue-1 are provided. Also provided are compositions containing these ligands as well as methods for administering these composi...

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Bibliographische Detailangaben
Hauptverfasser: JONES, STACEY, ANN, MALONEY, PATRICK, REED, GOODWIN, BRYAN, JAMES, KLIEWER, STEVEN, ANTHONY
Format: Patent
Sprache:eng ; fre
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