SOLUTION-PHASE COMBINATIORIAL LIBRARY SYNTHESIS AND PHARMACEUTICALLY ACTIVE COMPOUNDS PRODUCED THEREBY

The invention provides methods for solution-phase synthesis of nucleotide-based compounds and new libraries of such compounds. Compounds of the invention are useful for a variety of therapeutic applications, including treatment of viral or bacterial infections and associated diseases and disorders....

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Bibliographische Detailangaben
Hauptverfasser:	UPPENDRAN, SATHAYA, IYER, RADHAKRISHNAN, P, ZHOU, WENGING
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	The invention provides methods for solution-phase synthesis of nucleotide-based compounds and new libraries of such compounds. Compounds of the invention are useful for a variety of therapeutic applications, including treatment of viral or bacterial infections and associated diseases and disorders. L'invention concerne des procédés de synthèse en phase en solution de composés à base de nucléotides et de nouvelles bibliothèques desdits composés. Lesdits composés sont utilisés dans toute une variété d'applications thérapeutiques, comme le traitement d'infections virales ou bactériennes et des maladies et troubles liés à celles-ci.