PRE-S PROTEIN OF HEPATITIS B VIRUS (HBV) AS AN ADJUVANT AND A COMPONENT OF HBV VACCINE

The present invention relates to an adjuvant and vaccine composition containing pre-S of the hepatitis B virus, and more specifically to a modified recombinant pre-S that can enhance immunogenicity of a general vaccine antigen. The present invention also relates to an improved prophylactic Hepatitis...

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Bibliographische Detailangaben
Hauptverfasser:	PARK, JI-HEE, SEOMUN, YOUNG, YUM, JUNG-SUN, YI, SU-YOUNG, KIM, KI-YONG, MUN, HONG-MO, AHN, BYUNGOL
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to an adjuvant and vaccine composition containing pre-S of the hepatitis B virus, and more specifically to a modified recombinant pre-S that can enhance immunogenicity of a general vaccine antigen. The present invention also relates to an improved prophylactic Hepatitis B virus (HBV) vaccine and a therapeutic vaccine for the treatment of chronic HBV carriers. L'invention concerne une composition d'adjuvant et de vaccin contenant un pré-S du virus de l'hépatite B, et plus particulièrement un pré-S recombinant modifié, susceptible d'augmenter l'immunogénicité d'un antigène de vaccin général. La présente invention porte également sur un vaccin prophylactique amélioré contre le virus d'hépatite B (HBV) et sur un vaccin thérapeutique pour traiter les porteurs HBV chroniques.