GPE ANALOGS AND PEPTIDOMIMETICS

The invention relates to analogs and peptidomimetics of glycyl-L-prolyl-L-glutamic acid (GPE). In particular, this invention relates to GPE analogs and peptidomimetics that are anti-apoptotic and anti-necrotic, to methods of making them, to pharmaceutical compositions containing them, and to their u...

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Bibliographische Detailangaben
Hauptverfasser:	BRIMBLE, MARGARET, ANNE, ABOOD, NORMAN, A
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to analogs and peptidomimetics of glycyl-L-prolyl-L-glutamic acid (GPE). In particular, this invention relates to GPE analogs and peptidomimetics that are anti-apoptotic and anti-necrotic, to methods of making them, to pharmaceutical compositions containing them, and to their use. L'invention concerne des peptidomimétiques et des analogues d'acide glycyl-L-prolyl-L-glutamique (GPE). L'invention porte notamment sur des peptidomimétiques et sur des analogues de GPE qui sont anti-apoptotiques et anti-nécrotiques, sur leurs procédés de fabrication, sur des préparations pharmaceutiques les contenant et sur leur utilisation.