PHARMACEUTICALLY EFFECTIVE GINSENOSIDES AND THEIR USE

The invention provides use of panaxadiol for the treatment of conditions requiring stimulation of angiogenesis but not stimulation of chemoinvasion and use of panaxadiol in the manufacture of medicaments for treatment selected from the group consisting of promotion of late stage angiogenesis, mainte...

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Hauptverfasser: SENGUPTA, SHILADITYA, FAN, TAI-PING, TOH, SUE-ANNE EE SHIOW, LEUNG, HI, WUN, WONG, NGOK, SHUN, RICKY, YEUNG, HIN, WING
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention provides use of panaxadiol for the treatment of conditions requiring stimulation of angiogenesis but not stimulation of chemoinvasion and use of panaxadiol in the manufacture of medicaments for treatment selected from the group consisting of promotion of late stage angiogenesis, maintenance of established neo-vasculature, treatment of myocardial ischaemia, treatment of diabetic nephropathy, healing of diabetic ulcers or pressure ulcers, treatment of cerebrovascular ischaemia and angina, increase of graft or implant survival, promotion of bone growth, healing of fractures, and preventing hair loss by promoting or maintaining an existing angiogenic response. A preferred panaxadiol is the naturally occuring ginsenoside Rb1. L'invention concerne l'utilisation de panaxadiol pour le traitement de pathologies demandant une stimulation de l'angiogenèse mais non une stimulation de la chimioinvasion, ainsi que l'utilisation de panaxadiol pour la production de médicaments convenant pour de tels traitements. Le panaxadiol préféré est le ginsenoside Rb1 d'origine naturelle.