THIAZOLE AND OXAZOLE DERIVATIVES AS ACTIVATORS OF HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS

The present invention provides a compound of formula (I) wherein R>1525262< are defined as in claim 1. The compounds activate human peroxisome proliferator activated receptors (hPPARs) and are useful for the treatment of associated disorders such as cardiovascular disease and hypercholesteremi...

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Bibliographische Detailangaben
Hauptverfasser:	SZNAIDMAN, MARCOS, LUIS, STERNBACH, DANIEL, DAVID, CADILLA, RODOLFO, BANKER, PIERETTE, RAFFERTY, STEPHEN, WILLIAM, LAMBERT, MILLARD, HURST, III
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a compound of formula (I) wherein R>1525262< are defined as in claim 1. The compounds activate human peroxisome proliferator activated receptors (hPPARs) and are useful for the treatment of associated disorders such as cardiovascular disease and hypercholesteremia. L'invention concerne un composé représenté par la formule (I) : (I) dans laquelle R>1525262< répondent à leur définition de la revendication 1. Ces composés activent les récepteurs activés par le proliférateur du peroxysome humain (hPPARs) et sont utiles pour le traitement de maladies associées, telles que la maladie cardio-vasculaire et l'hypercholestérolémie.