COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF LUNG CANCER

Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such...

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Hauptverfasser:	VEDVICK, THOMAS, S, WANG, TONGTONG, MARNERAKIS, MARGARITA, CARTER, DARRICK, MCNEILL, PATRICIA, D, LI, SAMUEL, X, SKEIKY, YASIR, A., W, WATANABE, YOSHIHIRO, WANG, AIJUN, HENDERSON, ROBERT, A, KALOS, MICHAEL, D, FANGER, NEIL, RETTER, MARC, W, FANGER, GARY, RICHARD, PECKHAM, DAVID, W
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer. La présente invention concerne des compositions et des méthodes pour le traitement et le diagnostic du cancer, en particulier du cancer du poumon. Ces compositions renferment typiquement un ou plusieurs polypeptides de tumeur du poumon, des parties immunogènes de ces polypeptides, des polynucléotides codant pour de tels polypeptides, cellule présentatrice de l'antigène qui exprime de tels polypeptides, et des lymphocytes T qui sont spécifiques des cellules exprimant lesdits polypeptides. Les compositions selon l'invention conviennent notamment bien pour le diagnostic, la prévention et/ou le traitement de certaines maladies, en particulier du cancer du poumon.