SCREENING ASSAY METHODS AND SYSTEMS USING TARGET POOLING

Methods, devices and systems for increasing the throughput of screening assays by pooling multiple target systems, which allow a library of different materials, e.g., test compounds, to be screened against the pooled targets to determine whether any of the materials affect one or more of the target...

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Bibliographische Detailangaben
Hauptverfasser:	FARINAS, JAVIER, A, WADA, H., GARRETT
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING TRANSPORTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Methods, devices and systems for increasing the throughput of screening assays by pooling multiple target systems, which allow a library of different materials, e.g., test compounds, to be screened against the pooled targets to determine whether any of the materials affect one or more of the target systems. In preferred aspects, functioning of individual target systems is identified by differences in physical, chemical and/or optical properties particular to the target system in a target pool. La présente invention concerne des techniques, des dispositifs et des systèmes permettant d'augmenter la production des analyses de criblage par regroupement de multiples systèmes cible, ce qui permet de cribler une bibliothèque de différents matériaux, par exemple des composés test, contre les cibles regroupées de façon à déterminer si un de ces matériaux influence un ou plusieurs des systèmes cible. Dans des aspects préférés, on identifie le fonctionnement de systèmes cible individuels par des différences de propriétés physiques, chimiques et/ou optiques propres au système cible dans un regroupement cible.