Polypetides and corresponding molecules for disease detection and treatment

The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The inv...

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Hauptverfasser:	SPIRO, PETER, A, WRIGHT, RACHEL, J, BRADLEY, DIANA, L, DAM, TAM, C, ROSEN, BRUCE, H, STOCKDREHER, THERESA, K, DAFFO, ABEL, HILLMAN, JENNIFER L, PANZER, SCOTT, R, BRATCHER, SHAWN, R, JACKSON, STUART, CHALUP, MICHAEL, S, DANIELS, SUSAN, E, BANVILLE, STEVEN, C, AMSHEY, STEFAN, LINCOLN, STEPHEN, E, DUFOUR, GERARD, E, YU, JIMMY, Y, COHEN, HOWARD, J, SHAH, PURVI, CHEN, WENSHENG, RUSSO, FRANK, D, GREENAWALT, LILA, B, CHEN, ALICE, DAHL, CHRISTOPHER, R, CHANG, SIMON, ROSEBERRY, ANN, M, YAP, PIERRE, E, FONG, WILLY, T, LIU, TOMMY, F, HODGSON, DAVID, M, D'SA, STEVEN, A, FLORES, VINCENT, JONES, ANISSA, L
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides purified disease detection and treatment molecule polynucleotides (mddt). Also encompassed are the polypeptides (MDDT) encoded by mddt. The invention also provides for the use of mddt, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing mddt for the expression of MDDT. The invention additionally provides for the use of isolated and purified MDDT to induce anitbodies and to screen libraries of compounds and the use of anti-MDDT antibodies in diagnostic assays. Also provided are microarrays containing mddt and methods of use.