QUINOLONE COMPOUNDS FOR USE IN TREATING VIRAL INFECTIONS

The present invention relates to quinolone compounds, such as compounds of formula (Ia) wherein: R is hydrogen; R is oxygen or sulfur; R is trifluoromethyl; cyano; C1-8alkyl optionally substituted with C1-8alkyl or trifluoromethyl; or OR , wherein R is C1-8alkyl optionally substituted with C1-8alkyl...

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Hauptverfasser:	FREEMAN, GEORGE, ANDREW, HOPKINS, ANDREW, LEE, ANDREWS, CLARENCE, WEBSTER, III
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	FREEMAN, GEORGE, ANDREW HOPKINS, ANDREW, LEE ANDREWS, CLARENCE, WEBSTER, III
description	The present invention relates to quinolone compounds, such as compounds of formula (Ia) wherein: R is hydrogen; R is oxygen or sulfur; R is trifluoromethyl; cyano; C1-8alkyl optionally substituted with C1-8alkyl or trifluoromethyl; or OR , wherein R is C1-8alkyl optionally substituted with C1-8alkyl; R is OR , wherein R is C2-8alkenyl optionally substituted with C1-8alkyl; C1-8alkyl optionally substituted with C1-8alkyl; C6-14arylalkyl; C3-6cycloalkyl; C3-6cycloalkylalkyl; heterocyclealkyl; heterocyclealkynyl; C3-6cycloalkylalkenyl; C6-14arylalkynyl; C3-6cycloalkylalkynyl; SR , wherein R is C3-6cycloalkyl; S(O)R , wherein R is C3-6cycloalkyl; or NR R wherein R and R , which may be the same or different, are hydrogen or C1-8alkyl, optionally substituted with C1-8alkyl; R is hydrogen; nitro; halogen; C1-8alkyl, optionally substituted with C1-8alkyl or trifluoromethyl; R is hydrogen; halogen; C1-8alkyl; cyano: trifluoromethyl; or OR wherein R is C1-8alkyl or trifluoromethyl; R is hydrogen; C1-8alkyl; halogen; C6-14aryl; C1-8alkylaryl; C2-8alkynyl; heteroaryl; or OR wherein R is C1-8alkyl; R is hydrogen; halogen; cyano; nitro; or OR , wherein R is hydrogen or C1-8alkyl optionally substituted with C1-8alkyl or trifluoromethyl; and their use in the treatment of viral infections. The present invention relates to quinolone compounds and their use in the treatment of viral infections. La présente invention concerne des composés de quinolone et leur utilisation dans le traitement d'infections virales.
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The present invention relates to quinolone compounds and their use in the treatment of viral infections. La présente invention concerne des composés de quinolone et leur utilisation dans le traitement d'infections virales.</description><edition>7</edition><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2001</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20010628&DB=EPODOC&CC=WO&NR=0146150A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20010628&DB=EPODOC&CC=WO&NR=0146150A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FREEMAN, GEORGE, ANDREW</creatorcontrib><creatorcontrib>HOPKINS, ANDREW, LEE</creatorcontrib><creatorcontrib>ANDREWS, CLARENCE, WEBSTER, III</creatorcontrib><title>QUINOLONE COMPOUNDS FOR USE IN TREATING VIRAL INFECTIONS</title><description>The present invention relates to quinolone compounds, such as compounds of formula (Ia) wherein: R is hydrogen; R is oxygen or sulfur; R is trifluoromethyl; cyano; C1-8alkyl optionally substituted with C1-8alkyl or trifluoromethyl; or OR , wherein R is C1-8alkyl optionally substituted with C1-8alkyl; R is OR , wherein R is C2-8alkenyl optionally substituted with C1-8alkyl; C1-8alkyl optionally substituted with C1-8alkyl; C6-14arylalkyl; C3-6cycloalkyl; C3-6cycloalkylalkyl; heterocyclealkyl; heterocyclealkynyl; C3-6cycloalkylalkenyl; C6-14arylalkynyl; C3-6cycloalkylalkynyl; SR , wherein R is C3-6cycloalkyl; S(O)R , wherein R is C3-6cycloalkyl; or NR R wherein R and R , which may be the same or different, are hydrogen or C1-8alkyl, optionally substituted with C1-8alkyl; R is hydrogen; nitro; halogen; C1-8alkyl, optionally substituted with C1-8alkyl or trifluoromethyl; R is hydrogen; halogen; C1-8alkyl; cyano: trifluoromethyl; or OR wherein R is C1-8alkyl or trifluoromethyl; R is hydrogen; C1-8alkyl; halogen; C6-14aryl; C1-8alkylaryl; C2-8alkynyl; heteroaryl; or OR wherein R is C1-8alkyl; R is hydrogen; halogen; cyano; nitro; or OR , wherein R is hydrogen or C1-8alkyl optionally substituted with C1-8alkyl or trifluoromethyl; and their use in the treatment of viral infections. The present invention relates to quinolone compounds and their use in the treatment of viral infections. La présente invention concerne des composés de quinolone et leur utilisation dans le traitement d'infections virales.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2001</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLAIDPX08_fx93NVcPb3DfAP9XMJVnDzD1IIDXZV8PRTCAlydQzx9HNXCPMMcvQBiri5Ood4-vsF8zCwpiXmFKfyQmluBgU31xBnD93Ugvz41OKCxOTUvNSS-HB_A0MTM0NTA0cjYyKUAAAzIyhY</recordid><startdate>20010628</startdate><enddate>20010628</enddate><creator>FREEMAN, GEORGE, ANDREW</creator><creator>HOPKINS, ANDREW, LEE</creator><creator>ANDREWS, CLARENCE, WEBSTER, III</creator><scope>EVB</scope></search><sort><creationdate>20010628</creationdate><title>QUINOLONE COMPOUNDS FOR USE IN TREATING VIRAL INFECTIONS</title><author>FREEMAN, GEORGE, ANDREW ; HOPKINS, ANDREW, LEE ; ANDREWS, CLARENCE, WEBSTER, III</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO0146150A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2001</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>FREEMAN, GEORGE, ANDREW</creatorcontrib><creatorcontrib>HOPKINS, ANDREW, LEE</creatorcontrib><creatorcontrib>ANDREWS, CLARENCE, WEBSTER, III</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FREEMAN, GEORGE, ANDREW</au><au>HOPKINS, ANDREW, LEE</au><au>ANDREWS, CLARENCE, WEBSTER, III</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>QUINOLONE COMPOUNDS FOR USE IN TREATING VIRAL INFECTIONS</title><date>2001-06-28</date><risdate>2001</risdate><abstract>The present invention relates to quinolone compounds, such as compounds of formula (Ia) wherein: R is hydrogen; R is oxygen or sulfur; R is trifluoromethyl; cyano; C1-8alkyl optionally substituted with C1-8alkyl or trifluoromethyl; or OR , wherein R is C1-8alkyl optionally substituted with C1-8alkyl; R is OR , wherein R is C2-8alkenyl optionally substituted with C1-8alkyl; C1-8alkyl optionally substituted with C1-8alkyl; C6-14arylalkyl; C3-6cycloalkyl; C3-6cycloalkylalkyl; heterocyclealkyl; heterocyclealkynyl; C3-6cycloalkylalkenyl; C6-14arylalkynyl; C3-6cycloalkylalkynyl; SR , wherein R is C3-6cycloalkyl; S(O)R , wherein R is C3-6cycloalkyl; or NR R wherein R and R , which may be the same or different, are hydrogen or C1-8alkyl, optionally substituted with C1-8alkyl; R is hydrogen; nitro; halogen; C1-8alkyl, optionally substituted with C1-8alkyl or trifluoromethyl; R is hydrogen; halogen; C1-8alkyl; cyano: trifluoromethyl; or OR wherein R is C1-8alkyl or trifluoromethyl; R is hydrogen; C1-8alkyl; halogen; C6-14aryl; C1-8alkylaryl; C2-8alkynyl; heteroaryl; or OR wherein R is C1-8alkyl; R is hydrogen; halogen; cyano; nitro; or OR , wherein R is hydrogen or C1-8alkyl optionally substituted with C1-8alkyl or trifluoromethyl; and their use in the treatment of viral infections. The present invention relates to quinolone compounds and their use in the treatment of viral infections. La présente invention concerne des composés de quinolone et leur utilisation dans le traitement d'infections virales.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	QUINOLONE COMPOUNDS FOR USE IN TREATING VIRAL INFECTIONS
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