QUINOLONE COMPOUNDS FOR USE IN TREATING VIRAL INFECTIONS

The present invention relates to quinolone compounds, such as compounds of formula (Ia) wherein: R is hydrogen; R is oxygen or sulfur; R is trifluoromethyl; cyano; C1-8alkyl optionally substituted with C1-8alkyl or trifluoromethyl; or OR , wherein R is C1-8alkyl optionally substituted with C1-8alkyl; R is OR , wherein R is C2-8alkenyl optionally substituted with C1-8alkyl; C1-8alkyl optionally substituted with C1-8alkyl; C6-14arylalkyl; C3-6cycloalkyl; C3-6cycloalkylalkyl; heterocyclealkyl; heterocyclealkynyl; C3-6cycloalkylalkenyl; C6-14arylalkynyl; C3-6cycloalkylalkynyl; SR , wherein R is C3-6cycloalkyl; S(O)R , wherein R is C3-6cycloalkyl; or NR R wherein R and R , which may be the same or different, are hydrogen or C1-8alkyl, optionally substituted with C1-8alkyl; R is hydrogen; nitro; halogen; C1-8alkyl, optionally substituted with C1-8alkyl or trifluoromethyl; R is hydrogen; halogen; C1-8alkyl; cyano: trifluoromethyl; or OR wherein R is C1-8alkyl or trifluoromethyl; R is hydrogen; C1-8alkyl; halogen; C6-14aryl; C1-8alkylaryl; C2-8alkynyl; heteroaryl; or OR wherein R is C1-8alkyl; R is hydrogen; halogen; cyano; nitro; or OR , wherein R is hydrogen or C1-8alkyl optionally substituted with C1-8alkyl or trifluoromethyl; and their use in the treatment of viral infections. The present invention relates to quinolone compounds and their use in the treatment of viral infections. La présente invention concerne des composés de quinolone et leur utilisation dans le traitement d'infections virales.