A PHARMACEUTICAL DELIVERY SYSTEM FOR VITAMIN C AND VITAMIN E AND USE OF A COMBINATION OF VITAMIN C AND E FOR PREVENTING OR TREATING CONDITIONS INVOLVING OXIDATIVE STRESS
A pharmaceutical delivery system comprising a slow-release formulation of vitamin C (ascorbic acid) and a plain-release formulation of vitamin E (tocopherol) has been found to raise and maintain the concentrations of these vitamins in the blood plasma to a ratio of approximately 2.2:1. The steady-st...
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Zusammenfassung: | A pharmaceutical delivery system comprising a slow-release formulation of vitamin C (ascorbic acid) and a plain-release formulation of vitamin E (tocopherol) has been found to raise and maintain the concentrations of these vitamins in the blood plasma to a ratio of approximately 2.2:1. The steady-state concentration and ratio of these antioxidants has been found to be critical in the prevention and treatment of oxidative stress related disorders such as arteriosclerosis and diabetes and neural degenerative disorders such as Alzheimer's Disease.
L'invention concerne un système d'administration pharmaceutique qui comprend une préparation de vitamine C (acide ascorbique) à diffusion lente et une préparation à diffusion simple de vitamine E (tocophérol) qui s'est révélé efficace pour augmenter et stabiliser les concentrations de ces vitamines dans le plasma sanguin à un taux d'environ 2.2:1. La concentration permanente et le taux de ces antioxydants s'avèrent importants dans la prévention et le traitement du stress oxydatif lié aux troubles tels que l'artériosclérose, le diabète et les troubles dégénérescents neuronaux comme la maladie d'Alzheimer. |
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