DRUG RELEASING BIODEGRADABLE FIBER IMPLANT
The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise biodegradable polymer fibers capable of the controlled delivery of therapeutic agents. The spatial and temporal dis...
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| creator | ROMERO-SANCHEZ, ANDRES, A., A RADULESCU, DELIA WAGGONER, PAULA SMITH, GEORGE, M ALIKACEM, NADIR HU, ZHIBING NELSON, KEVIN, D |
| description | The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise biodegradable polymer fibers capable of the controlled delivery of therapeutic agents. The spatial and temporal distribution of released therapeutic agents is controlled by use of defined nonhomogeneous patterns of therapeutic agents in the matrices.
L'invention concerne des compositions de génie tissulaire et des procédés associés. Des matrices tridimensionnelles pour cultiver des cellules sont préparées pour utilisation in vitro et in vivo. Ces matrices comportent des fibres polymères biodégradables capables de libérer des agents thérapeutiques. La distribution spatiale et temporelle des agents thérapeutiques libérés est régulée par l'emploi de motifs non homogènes d'agents thérapeutiques dans les matrices. |
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L'invention concerne des compositions de génie tissulaire et des procédés associés. Des matrices tridimensionnelles pour cultiver des cellules sont préparées pour utilisation in vitro et in vivo. Ces matrices comportent des fibres polymères biodégradables capables de libérer des agents thérapeutiques. La distribution spatiale et temporelle des agents thérapeutiques libérés est régulée par l'emploi de motifs non homogènes d'agents thérapeutiques dans les matrices.</description><edition>7</edition><language>eng ; fre</language><subject>APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBONFILAMENTS ; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS,THREADS, FIBRES, BRISTLES OR RIBBONS ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR ; HUMAN NECESSITIES ; HYGIENE ; LAUNDERING ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ; NATURAL OR ARTIFICIAL THREADS OR FIBRES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPINNING ; TEXTILES ; TREATMENT OF TEXTILES OR THE LIKE ; TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS,FABRICS, FEATHERS, OR FIBROUS GOODS MADE FROM SUCH MATERIALS</subject><creationdate>2001</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20010215&DB=EPODOC&CC=WO&NR=0110421A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20010215&DB=EPODOC&CC=WO&NR=0110421A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ROMERO-SANCHEZ, ANDRES, A., A</creatorcontrib><creatorcontrib>RADULESCU, DELIA</creatorcontrib><creatorcontrib>WAGGONER, PAULA</creatorcontrib><creatorcontrib>SMITH, GEORGE, M</creatorcontrib><creatorcontrib>ALIKACEM, NADIR</creatorcontrib><creatorcontrib>HU, ZHIBING</creatorcontrib><creatorcontrib>NELSON, KEVIN, D</creatorcontrib><title>DRUG RELEASING BIODEGRADABLE FIBER IMPLANT</title><description>The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise biodegradable polymer fibers capable of the controlled delivery of therapeutic agents. The spatial and temporal distribution of released therapeutic agents is controlled by use of defined nonhomogeneous patterns of therapeutic agents in the matrices.
L'invention concerne des compositions de génie tissulaire et des procédés associés. Des matrices tridimensionnelles pour cultiver des cellules sont préparées pour utilisation in vitro et in vivo. Ces matrices comportent des fibres polymères biodégradables capables de libérer des agents thérapeutiques. La distribution spatiale et temporelle des agents thérapeutiques libérés est régulée par l'emploi de motifs non homogènes d'agents thérapeutiques dans les matrices.</description><subject>APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBONFILAMENTS</subject><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</subject><subject>CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS,THREADS, FIBRES, BRISTLES OR RIBBONS</subject><subject>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</subject><subject>FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>LAUNDERING</subject><subject>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><subject>NATURAL OR ARTIFICIAL THREADS OR FIBRES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPINNING</subject><subject>TEXTILES</subject><subject>TREATMENT OF TEXTILES OR THE LIKE</subject><subject>TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS,FABRICS, FEATHERS, OR FIBROUS GOODS MADE FROM SUCH MATERIALS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2001</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNByCQp1Vwhy9XF1DPb0c1dw8vR3cXUPcnRxdPJxVXDzdHINUvD0DfBx9AvhYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXx4f4GhoYGJkaGjobGRCgBAPZDJAs</recordid><startdate>20010215</startdate><enddate>20010215</enddate><creator>ROMERO-SANCHEZ, ANDRES, A., A</creator><creator>RADULESCU, DELIA</creator><creator>WAGGONER, PAULA</creator><creator>SMITH, GEORGE, M</creator><creator>ALIKACEM, NADIR</creator><creator>HU, ZHIBING</creator><creator>NELSON, KEVIN, D</creator><scope>EVB</scope></search><sort><creationdate>20010215</creationdate><title>DRUG RELEASING BIODEGRADABLE FIBER IMPLANT</title><author>ROMERO-SANCHEZ, ANDRES, A., A ; RADULESCU, DELIA ; WAGGONER, PAULA ; SMITH, GEORGE, M ; ALIKACEM, NADIR ; HU, ZHIBING ; NELSON, KEVIN, D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO0110421A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2001</creationdate><topic>APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBONFILAMENTS</topic><topic>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</topic><topic>CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS,THREADS, FIBRES, BRISTLES OR RIBBONS</topic><topic>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</topic><topic>FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>LAUNDERING</topic><topic>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</topic><topic>NATURAL OR ARTIFICIAL THREADS OR FIBRES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPINNING</topic><topic>TEXTILES</topic><topic>TREATMENT OF TEXTILES OR THE LIKE</topic><topic>TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS,FABRICS, FEATHERS, OR FIBROUS GOODS MADE FROM SUCH MATERIALS</topic><toplevel>online_resources</toplevel><creatorcontrib>ROMERO-SANCHEZ, ANDRES, A., A</creatorcontrib><creatorcontrib>RADULESCU, DELIA</creatorcontrib><creatorcontrib>WAGGONER, PAULA</creatorcontrib><creatorcontrib>SMITH, GEORGE, M</creatorcontrib><creatorcontrib>ALIKACEM, NADIR</creatorcontrib><creatorcontrib>HU, ZHIBING</creatorcontrib><creatorcontrib>NELSON, KEVIN, D</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ROMERO-SANCHEZ, ANDRES, A., A</au><au>RADULESCU, DELIA</au><au>WAGGONER, PAULA</au><au>SMITH, GEORGE, M</au><au>ALIKACEM, NADIR</au><au>HU, ZHIBING</au><au>NELSON, KEVIN, D</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DRUG RELEASING BIODEGRADABLE FIBER IMPLANT</title><date>2001-02-15</date><risdate>2001</risdate><abstract>The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise biodegradable polymer fibers capable of the controlled delivery of therapeutic agents. The spatial and temporal distribution of released therapeutic agents is controlled by use of defined nonhomogeneous patterns of therapeutic agents in the matrices.
L'invention concerne des compositions de génie tissulaire et des procédés associés. Des matrices tridimensionnelles pour cultiver des cellules sont préparées pour utilisation in vitro et in vivo. Ces matrices comportent des fibres polymères biodégradables capables de libérer des agents thérapeutiques. La distribution spatiale et temporelle des agents thérapeutiques libérés est régulée par l'emploi de motifs non homogènes d'agents thérapeutiques dans les matrices.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBONFILAMENTS CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS,THREADS, FIBRES, BRISTLES OR RIBBONS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR HUMAN NECESSITIES HYGIENE LAUNDERING MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL NATURAL OR ARTIFICIAL THREADS OR FIBRES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPINNING TEXTILES TREATMENT OF TEXTILES OR THE LIKE TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS,FABRICS, FEATHERS, OR FIBROUS GOODS MADE FROM SUCH MATERIALS |
| title | DRUG RELEASING BIODEGRADABLE FIBER IMPLANT |
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