3-BICYCLOARYL-2-AMINOMETHYL BICYCLOALKANES AS SEROTONINE REUPTAKE INHIBITORS

A pharmaceutical compound of formula (I) in which R and R are each hydrogen or C1-4 alkyl, or R and R together with the nitrogen atom to which they are attached form an azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl or morpholino group, said group being optionally substituted with 1 to 3 C1-4 al...

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Bibliographische Detailangaben
Hauptverfasser:	TUPPER, DAVID, EDWARD, MILUTINOVIC, SANDRA, GINETTE, KEENAN, MARTINE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	A pharmaceutical compound of formula (I) in which R and R are each hydrogen or C1-4 alkyl, or R and R together with the nitrogen atom to which they are attached form an azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl or morpholino group, said group being optionally substituted with 1 to 3 C1-4 alkyl substituents, R is a naphthyl, indolyl, benzothienyl, benzofuranyl, benzothiazolyl, quinolinyl or isoquinolinyl group, said group being optionally substituted, and n is 1 or 2; or a salt or ester thereof. L'invention concerne un composé pharmaceutique de la formule (I), dans laquelle R et R représentent, chacun, un hydrogène ou un C1-4 alkyle, ou R et R ainsi que l'atome d'azote auquel ils sont fixés forment un groupe azétidinyle, pyrrolidinyle, pipéridinyle, pipérazinyle ou morpholino, ledit groupe étant facultativement substitué avec 1 à 3 substituants C1-4 alkyle; R est un groupe naphtyle, indolyle, benzothiényle, benzofuranyle, benzothiazolyle, quinolinyle ou isoquinolinyle, ledit groupe étant facultativement substitué, et n est égal à 1 ou 2; ou un sel ou un ester de ces derniers.