COMPUESTOS DE 4-METILPIRIDOPIRIMIDINONA

La presente invencion se refiere a compuestos novedoso de 4-metilpiridopirimidinonna de formula (I), y a las sales de los mismos, su síntesis, y su uso como inhibidores de la fosfoinositido 3-quinasa alfa (P13-Ka(alfa)). The present invention is directed to novel 4-methylpyridopyrimidinone compounds...

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Bibliographische Detailangaben
Hauptverfasser:	DILIP BHUMRALKAR, ROBERT STEVEN KANIA, MITCHELL DAVID NAMBU, MICHAEL BRUNO PLEWE, MARY CATHERINE JOHNSON, MASON ALAN PAIRISH, JACQUI ELIZABETH HOFFMAN, KHANH TUAN TRAN, PHUONG THI QUY LE, KLAUS RUPRECHT DRESS, HENGMIAO CHENG
Format:	Patent
Sprache:	spa
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	La presente invencion se refiere a compuestos novedoso de 4-metilpiridopirimidinonna de formula (I), y a las sales de los mismos, su síntesis, y su uso como inhibidores de la fosfoinositido 3-quinasa alfa (P13-Ka(alfa)). The present invention is directed to novel 4-methylpyridopyrimidinone compounds of Formula (I), and to salts thereof, their synthesis, and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3-Kalpha).