Macrocyclic inhibitors of flaviviridae viruses

Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.

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Bibliographische Detailangaben
Hauptverfasser: Schrier, Adam James, Highton, Adrian John, Aciro, Caroline, Steadman, Victoria Alexandra, Chiva, Jean Yves, Dunbar, Neil Andrew, Mackman, Richard, Poullennec, Karine G, Lazarides, Linos, Karki, Kapil Kumar, Jansa, Petr, Keats, Andrew John, Pettit, Simon Neil, Dean, David Kenneth, Siegel, Dustin Scott
Format: Patent
Sprache:eng
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Zusammenfassung:Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of virus infections, particularly hepatitis C infections.